abstract：:One hundred and eleven children admitted with suspected gastro-oesophageal reflux were studied, with 24 hour oesophageal pH monitoring as the first line of investigation. Barium swallow examination, or oesophagoscopy, or both, were carried out only in children with abnormal pH, who subsequently had a trial of 1-12 mon...

journal_title：Archives of disease in childhood

authors： Da Dalt L,Mazzoleni S,Montini G,Donzelli F,Zacchello F

更新日期：1989-10-01 00:00:00

abstract：:We recorded the respiratory history by questionnaire in a 7 year old cohort of children whose birth weight was under 2000 g and an unselected reference group of local schoolchildren of the same age. Complete data were obtained in 121 low birthweight children (90% of those studied): 62 who had no neonatal respiratory i...

journal_title：Archives of disease in childhood

authors： Chan KN,Elliman A,Bryan E,Silverman M

更新日期：1989-09-01 00:00:00

abstract：:The output of the drug and the particle size produced by various nebulisers were assessed, and sensible nebulisation times for sodium cromoglycate calculated. Three of the four nebuliser systems tested produced over 80% of total drug output within the first five minutes of nebulisation. We suggest that five minutes is...

journal_title：Archives of disease in childhood

authors： O'Callaghan C,Clark AR,Milner AD

更新日期：1989-09-01 00:00:00

abstract：:Thirty jaundiced neonates with diarrhoea who were being treated with phototherapy and 30 matched control infants were studied to try and find out the cause of the diarrhoea. Faecal osmolality and electrolyte concentrations were measured, which gave clear evidence that the diarrhoea arose from intestinal secretion. Rec...

journal_title：Archives of disease in childhood

authors： De Curtis M,Guandalini S,Fasano A,Saitta F,Ciccimarra F

更新日期：1989-08-01 00:00:00

abstract：:We investigated the associations between albuminuria, metabolic control, glomerular filtration, blood pressure, and platelet function in children with insulin dependent diabetes mellitus. The geometric mean (95% tolerance levels) albumin excretion (expressed as the geometric mean albumin to creatinine ratio on two ove...

journal_title：Archives of disease in childhood

authors： Gibb DM,Dunger D,Levin M,Shah V,Smith C,Barratt TM

更新日期：1989-07-01 00:00:00

abstract：:Endogenous formation of thromboxane A2 and prostacyclin were evaluated in seven neonatates with persistent pulmonary hypertension by serial gas chromatographic mass spectrometric determination of their urinary metabolites dinor-thromboxane B2 and dinor-6-keto-prostaglandin F1 alpha, respectively. The patients were stu...

journal_title：Archives of disease in childhood

authors： Kühl PG,Cotton RB,Schweer H,Seyberth HW

更新日期：1989-07-01 00:00:00

abstract：:The variability of cerebral blood flow velocity was measured in 20 very low birthweight infants. The area under the curve of the Doppler frequency spectrum was used and was obtained from the anterior cerebral artery in the infants before and after infusions of plasma or dopamine. Both interventions significantly reduc...

journal_title：Archives of disease in childhood

authors： Rennie JM

更新日期：1989-07-01 00:00:00

abstract：:To test whether early treatment could postpone the chronic colonisation of the respiratory tract with mucoid strains of Pseudomonas aeruginosa in patients with cystic fibrosis, we performed a pilot study in 28 patients aged 2 to 18 years. A two week course of azlocillin (150 mg/kg/day) and tobramycin (10 to 15 mg/kg/d...

journal_title：Archives of disease in childhood

authors： Steinkamp G,Tümmler B,Malottke R,von der Hardt H

更新日期：1989-07-01 00:00:00

abstract：:A 12 year old boy presented with primary nocturnal enuresis. Investigation showed extensive bilateral nephrocalcinosis of no obvious or recognised cause. Persistent severe renal hypercalciuria was confirmed by an intravenous calcium infusion. Idiopathic hypercalciuria is not a common cause of nephrocalcinosis and has ...

journal_title：Archives of disease in childhood

authors： Aggarwal VK,Jones KV

更新日期：1989-07-01 00:00:00

abstract：:A 9 month old boy presented with acute respiratory distress and was found to have a left pleural effusion. The chylous nature of the effusion, multiple bony lytic lesions, and splenic cysts lead to the diagnosis of congenital lymphangiomatosis with chylothorax. Surgical intervention including pleurectomy was required ...

journal_title：Archives of disease in childhood

authors： Dunkelman H,Sharief N,Berman L,Ninan T

更新日期：1989-07-01 00:00:00

abstract：:The first case of collagenous colitis in a child with protracted watery diarrhoea and abdominal pain is reported. Small bowel investigations and the macroscopic appearances were normal, but histological examination of the colon showed collagenous colitis. Steroids temporarily relieved the diarrhoea and induced transie...

journal_title：Archives of disease in childhood

authors： Perisic VN,Kokai G

更新日期：1989-06-01 00:00:00

abstract：:Cellobiose and mannitol absorption were studied in patients with suspected abnormal function of the small bowel mucosa. The urinary cellobiose:mannitol ratio was increased in subtotal villous atrophy, iron deficiency anaemia, and small intestinal Crohn's disease. The test seems a sensitive indicator of the integrity o...

journal_title：Archives of disease in childhood

authors： Hodges S,Ashmore SP,Patel HR,Tanner MS

更新日期：1989-06-01 00:00:00

abstract：:A longitudinal evaluation was carried out of the clinical, infective, and immunological progress of 34 children (who were aged 6 to 68 months--mean 25 months at the time of writing) born to 31 mothers infected with human immunodeficiency virus (HIV), over a mean observation period of 13.4 months. Clinical symptoms, no...

journal_title：Archives of disease in childhood

authors： Nadal D,Hunziker UA,Schüpbach J,Wetzel JC,Tomasik Z,Jendis JB,Fanconi A,Seger RA

更新日期：1989-05-01 00:00:00

abstract：:We studied two neonates fed diluted formula and excessive water who developed hyponatraemic convulsions; treatment included intravenous hypertonic saline and water restriction. Educating mothers is important to stop recurrences. ...

journal_title：Archives of disease in childhood

authors： Vanapruks V,Prapaitrakul K

更新日期：1989-05-01 00:00:00

abstract：:Ninety one patients with urinary tract abnormalities diagnosed before birth were reviewed. Diagnoses based on prenatal and postnatal ultrasound scans alone were compared with the final diagnoses after full urological investigations, with operative or necropsy confirmation in 79 cases. The results confirmed that ultras...

journal_title：Archives of disease in childhood

authors： Clarke NW,Gough DC,Cohen SJ

更新日期：1989-04-01 00:00:00

abstract：:An infant with chronic cytomegalovirus hepatitis and a child with atypical Alagille's syndrome had vitamin D deficiency rickets due to malabsorption. Both received ultraviolet irradiation. This treatment corrected biochemical abnormalities and healed the rickets. In the infant use of a sunlamp at home maintained norma...

journal_title：Archives of disease in childhood

authors： Kooh SW,Roberts EA,Fraser D,Curtis J,Jones G,Weber JL,Reilly BJ

更新日期：1989-04-01 00:00:00

abstract：:Transcutaneous Doppler ultrasound measurements were made of the superior mesenteric artery of 22 preterm infants (mean birth weight 600-2580 g) to investigate the response of intestinal blood flow to feeding. Analysis of the data in relation to milk intake showed a significant change in peak velocity and mean velocity...

journal_title：Archives of disease in childhood

authors： Leidig E

更新日期：1989-04-01 00:00:00

abstract：:The incidence of minor congenital anomalies was examined in 36 patients with ataxic cerebral palsy, in unaffected family members, and in 100 unrelated control subjects. None of the control subjects or family members had more than four anomalies, and 25 of 36 (69%) of the patients had more than four. The distribution o...

journal_title：Archives of disease in childhood

authors： Miller G

更新日期：1989-04-01 00:00:00

abstract：:Four Asian babies were investigated because they failed to thrive. In all four cases the failure to thrive was a result of the mother's social isolation and inability to communicate, and to the father's refusal to accept that there was a problem in the family. ...

journal_title：Archives of disease in childhood

authors： Fenton TR,Bhat R,Davies A,West R

更新日期：1989-03-01 00:00:00

abstract：:Determinations of body height and calculations of growth velocity are still the major parameters for the assessment of normal and aberrant growth. The present study was performed to investigate the minimum time interval between consecutive measurements that is necessary for a statement on significant length increment ...

journal_title：Archives of disease in childhood

authors： Hermanussen M,Burmeister J

更新日期：1989-02-01 00:00:00

abstract：:The prevalence of wheezing, 'asthma', treatment for 'asthma', and school absence as a result of wheezing in Nottingham was calculated from a questionnaire survey of parents of 4750 children in a random sample of primary schools. A response was achieved for 3805 (80%) children of whom 438 (11.5%) had had episodes of wh...

journal_title：Archives of disease in childhood

authors： Hill RA,Standen PJ,Tattersfield AE

更新日期：1989-02-01 00:00:00

abstract：:Doppler ultrasound measurements of pulmonary blood flow in 20 babies with severe respiratory distress syndrome treated in a randomised controlled trial of surfactant replacement showed that the immediate improvement of oxygenation was not associated with a significant increase in pulmonary blood flow. Reduction in ven...

journal_title：Archives of disease in childhood

authors： Halliday HL,McCord FB,McClure BG,Reid MM

更新日期：1989-01-01 00:00:00

abstract：:A study of staff stress and job satisfaction was undertaken in a children's hospice. In addition factors were investigated which might be stressful or which helped staff to manage in difficult circumstances. Three quarters were under comparatively little stress and in general showed very few psychological symptoms but...

journal_title：Archives of disease in childhood

authors： Woolley H,Stein A,Forrest GC,Baum JD

更新日期：1989-01-01 00:00:00

abstract：:By means of a simple questionnaire and measurements of height, weight, and peak expiratory flow rates 3061 children from city and rural populations were studied. Children with asthma or other respiratory diseases had lower peak expiratory flow rates, and younger children living in rural areas had higher rates. In 2828...

journal_title：Archives of disease in childhood

authors： Carson JW,Hoey H,Taylor MR

更新日期：1989-01-01 00:00:00

abstract：:Thirty six children with typical features of Angelman's syndrome, including global developmental delay, ataxia, episodes of paroxysmal laughter, seizures, and microcephaly were studied. The series included three sibships of three affected sisters, two affected brothers, and two affected sisters, respectively. The faci...

journal_title：Archives of disease in childhood

authors： Robb SA,Pohl KR,Baraitser M,Wilson J,Brett EM

更新日期：1989-01-01 00:00:00

abstract：:A four year regional screening programme to detect cystic fibrosis using measurement of immunoreactive trypsinogen is described. During this period 60 infants were diagnosed; 34 by screening, 12 born with meconium ileus, and 14 not identified by the screening assay but who presented with clinical symptoms at a later a...

journal_title：Archives of disease in childhood

authors： Roberts G,Stanfield M,Black A,Redmond A

更新日期：1988-12-01 00:00:00

abstract：:Three children with cystic fibrosis developed steatorrhoea unresponsive to changes in pancreatic supplements. The final diagnoses were chronic giardiasis, stagnant loop syndrome, and Crohn's disease. Refractory intestinal symptoms in cystic fibrosis merit further investigation. ...

journal_title：Archives of disease in childhood

authors： Baxter PS,Dickson JA,Variend S,Taylor CJ

更新日期：1988-12-01 00:00:00

abstract：:Mechanisms of gastro-oesophageal reflux were studied by oesophageal manometry and pH monitoring in 33 children: nine controls, 15 with gastro-oesophageal reflux alone, and nine with reflux oesophagitis. A total of 122 episodes of reflux were analysed in detail: 82 (67%) were synchronous with swallowing and 40 (33%) as...

journal_title：Archives of disease in childhood

authors： Mahony MJ,Migliavacca M,Spitz L,Milla PJ

更新日期：1988-11-01 00:00:00

abstract：:Eighty four very low birthweight babies (considered high risk for developing necrotising enterocolitis) were given vancomycin orally for 48 hours before introduction of oral feeds; one developed necrotising enterocolitis. One hundred and twenty very low birthweight babies (not considered such high risk) were fed witho...

journal_title：Archives of disease in childhood

authors： Ng PC,Dear PR,Thomas DF

更新日期：1988-11-01 00:00:00

abstract：:Ten patients with biotinidase deficiency were studied. Clinical findings at presentation varied with dermatological signs (dermatitis and alopecia), neurological abnormalities (fits, hypotonia, and ataxia), and recurrent infections being the most common features, although none of these occurred in every case. Biochemi...

journal_title：Archives of disease in childhood

authors： Wastell HJ,Bartlett K,Dale G,Shein A

更新日期：1988-10-01 00:00:00

abstract：:A neonate developed complete thrombosis of the abdominal aorta after catheterisation of the umbilical artery. This was successfully treated with an intravenous infusion of streptokinase. ...

journal_title：Archives of disease in childhood

authors： Kirk CR,Bhrolchain CN,Qureshi SA

更新日期：1988-09-01 00:00:00

abstract：:We report three cases of Hurler's disease in which glaucoma developed in early childhood. We draw attention to the fact that glaucoma may be a commonly unrecognised early complication of this condition. ...

journal_title：Archives of disease in childhood

authors： Nowaczyk MJ,Clarke JT,Morin JD

更新日期：1988-09-01 00:00:00

abstract：:Most of the consequences of early intercourse affect the woman and much research has focused upon her. As part of a study on teenage pregnancy, where 137 women were interviewed, 46 men were also interviewed. They were less likely to have had teaching about sex from parents and were subject to less parental supervision...

journal_title：Archives of disease in childhood

authors： Curtis HA,Tripp JH,Lawrence C,Clarke WL

更新日期：1988-08-01 00:00:00

abstract：:Rubella vaccination was offered to a cohort of schoolgirls 14 years and over whose immune state was unknown. This increased the percentage vaccinated or known to be immune from 86% to 90%. It is recommended that rubella vaccination should be offered to girls until they leave school at 16 years of age. ...

journal_title：Archives of disease in childhood

authors： Hodes DT

更新日期：1988-08-01 00:00:00

abstract：:We studied the effects on the family of childhood chronic renal failure by contrasting children with varying degrees of severity of illness with healthy controls. Disruption of family life was most common in families with the more severely ill children (on hospital haemodialysis) and there was a tendency for more ment...

journal_title：Archives of disease in childhood

authors： Reynolds JM,Garralda ME,Jameson RA,Postlethwaite RJ

更新日期：1988-07-01 00:00:00

abstract：:Two neonates with acute infantile cerebral Gaucher's disease had prominent collodion skin. Ichthyosis has been described in some cases of metabolic lipid disorders, however, this is the first report of the association of lamellar desquamation of the newborn (collodion baby) with Gaucher's disease. ...

journal_title：Archives of disease in childhood

authors： Lui K,Commens C,Choong R,Jaworski R

更新日期：1988-07-01 00:00:00

abstract：:A method for securing umbilical catheters is described. It has been used successfully in over 350 babies. It is a simple and rapid method that allows for easy repositioning and, unlike some established techniques, has no potential for damage to the preterm baby's skin. ...

journal_title：Archives of disease in childhood

authors： South M,Magnay A

更新日期：1988-07-01 00:00:00

abstract：:Flow velocities in the basal cerebral arteries were studied by transcranial Doppler sonography. A longitudinal study was undertaken on 25 healthy newborn babies during the first 20 days of life, and a cross sectional study was performed on 112 healthy children between 1 day and 18 years of age. A rapid linear increase...

journal_title：Archives of disease in childhood

authors： Bode H,Wais U

更新日期：1988-06-01 00:00:00

abstract：:The concentration of 27 amino acids in the vitreous humour was analysed in 120 cot deaths. Baseline data for age and postmortem interval are presented and the concentrations compared with the normal reference range for plasma. The results do not indicate that a specific aminoacidopathy is a factor in cot deaths. ...

journal_title：Archives of disease in childhood

authors： Patrick WJ,Logan RW

更新日期：1988-06-01 00:00:00

abstract：:The clinical response to sodium cromoglycate treatment was compared with its concentration in serum. Twenty five children with asthma entered a 10 week trial of two baseline weeks followed by eight weeks of treatment by the inhalation of 20 mg of sodium cromoglycate spincaps four times a day. Individual clinical respo...

journal_title：Archives of disease in childhood

authors： Yahav Y,Dany S,Katznelson D,Farfel Z

更新日期：1988-06-01 00:00:00